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pentobarbital will reduce the extent or impact of elbasvir/grazoprevir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic influence of elbasvir/grazoprevir could be decreased if coadministered with solid CYP3A inducers and is hence contraindicated.GABA, the major inhibitory neurotransmitter during the vertebr